Metastases of Merkel cell carcinoma in terms of diagnosing carcinomas with unknown primary localization.

Recurrent Merkel cell carcinoma of the testis with unknown primary site: a case report

BACKGROUND Merkel cell carcinoma is a rare and aggressive neuroendocrine tumor that commonly arises in the skin. It is rare for it to occur in the testes. There are only seven cases of testicular Merkel cell carcinoma reported in the literature. CASE PRESENTATION A 66-year-old Maori man presented to our hospital with left testicular swelling. His alpha-fetoprotein and beta-human chorionic gon...

Hepatic metastases from carcinomas of unknown primary site.

AIM Hepatic metastases are often present at diagnosis of carcinoma of unknown primary site (CUP). The objective of this study was to describe the diagnostic and therapeutic strategies used. METHODS One hundred and eighteen patients were treated at the Cancer Center of Montpellier from 1993 to 2002 for CUP initially metastatic to the liver. Initial characteristics, diagnostic tests, chemothera...

Primary Cutaneous Neuroendocrine Carcinoma , Merkel Cell Carcinoma .

Prognostic Factors in Primary Merkel Cell Carcinoma

Finland Academic dissertation To be publicly discussed, with the permission of the medical Faculty of the University of This thesis is based on the following original articles, which are referred to in the text by their Roman numerals. Some unpublished data are also presented.

Tenascin-C in primary Merkel cell carcinoma.

BACKGROUND/AIMS Merkel cell carcinoma (MCC) is a rare malignant cutaneous neuroendocrine tumour that mostly affects the elderly. It shows rapid progression of the primary tumour, together with a vertical growth pattern into the underlying subcutaneous tissue. Metastatic dissemination to regional lymph nodes is early and frequent. Tenascin-C (Tn-C) is a large extracellular matrix glycoprotein th...